PD09-01 ADVANCED PATERNAL AGE AFFECTS EMBRYO ANEUPLOIDY IN EGG DONOR CYCLES
نویسندگان
چکیده
منابع مشابه
High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles
OBJECTIVE Advanced paternal age is related to poor sperm quality; however, little is known on its effect on aneuploidy embryo rates and, more importantly, on chromosomal abnormalities like trisomy 21, 18 and 13. The objective of this study was to evaluate the effect of advanced paternal age on the trisomy rates of the chromosomes 21, 18 or 13 in embryos obtained from donated oocytes. METHODS ...
متن کاملHigh Aneuploidy Rates Observed in Embryos Derived from Donated Oocytes are Related to Male Aging and High Percentages of Sperm DNA Fragmentation
CAPSULE Male aging effects on aneuploidy rates in embryos. OBJECTIVE Paternal age is associated with decreasing sperm quality; however, it is unknown if it influences chromosomal abnormalities in embryos. The objective of this study is to evaluate if the aneuploidy rates in embryos are affected by advanced paternal age. METHODS A total of 286 embryos, obtained from 32 in vitro fertilization...
متن کاملAdvanced paternal age and reproductive outcome.
Women have been increasingly delaying the start of motherhood in recent decades. The same trend is seen also for men. The influence of maternal age on fertility, chromosomal anomalies, pregnancy complications, and impaired perinatal and post-natal outcome of offspring, has been thoroughly investigated, and these aspects are clinically applied during fertility and pregestational counseling. Male...
متن کاملUtilizing FMR1 Gene Mutations as Predictors of Treatment Success in Human In Vitro Fertilization
CONTEXT Mutations of the fragile X mental retardation 1 (FMR1) gene are associated with distinct ovarian aging patterns. OBJECTIVE To confirm in human in vitro fertilization (IVF) that FMR1 affects outcomes, and to determine whether this reflects differences in ovarian aging between FMR1 mutations, egg/embryo quality or an effect on implantation. DESIGN, SETTING, PATIENTS IVF outcomes were ...
متن کاملP-144: Egg and Embryo Donor's Application Forms in Infertility Centers; Medical, Genetic and Psychosocially Forms in Evaluating Potential Donor Candidate
Background: Nowadays, gamete and embryo donation is applied as effective process in treatment infertility problems. In order to participate in the process of donation, donors should complete an extensive questionnaire that details their personal and family medical history. Included in this questionnaire should be a detailed sexual history, substance abuse history, history of family disease, and...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2018
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2018.02.598